dv said:

The members of this crew are already the first people to get past low earth orbit in more than 50 years.

From the ISS you can see a patch of the Earth maybe 4000 km wide. The Artemis II folks can see very nearly half the globe.

And they’re expected to reach the furthest distance from Earth of any humans to date, as their trip around the moon will be from a greater distance from the lunar surface than the Apollo astronauts.